ESR 7: Design of antimicrobial mechanism of metallic patterned hydrophobic surfaces produced by dealloying and plastic flow deformation of metallic glasses
- Host institution: Università degli Studi di Torino (UNITO), Italy
- Supervisor: Prof. Paola Rizzi (paola.rizzi(at)unito.it)
- ESR 7: Kirti Tiwari (kirti.tiwari(at)unito.it)
Project Description
Objectives: Design antimicrobial TiO2, Cu or Au nanostructured surfaces with direct topological action and/or enhanced chemical activity in influencing antibacterial surface properties and evaluation of their surface microbial adhesion. Tasks: i) development of new Ti-Cu based amorphous alloys with antimicrobial elements (Ag, Ga or Zn); ii) design of nanoporous Cu/TiO2 surfaces from Ti-based glassy alloys, development of hierarchical nanopatterned surfaces by plastic flow deformation and dealloying whit the evaluation of surface wettability of the produced materials; iii) evaluation, in cell free systems, of antimicrobial activity by: reactive oxygen species, Fenton chemistry, free-radical release, surface radical species, peroxidation of biomolecules, including endogenous antioxidants and/or suitable molecular probes.
Expected Results: Development of efficient nanoporous hydrophobic surfaces on glassy alloys.
The ESR will travel abroad for research secondments at partner organisations of the BIOREMIA Network (e.g. at IFW Dresden-Germany, Universitat Autonoma de Barcelona-Spain, The University Clinics of Giessen & Marburg - Germany, PX Services-Switzerland) and will participate in specialised training meetings and international conferences.
ESR 7: Kirti Tiwari
![](/fileadmin/bioremia/fellows/esr-7-kirti.jpg)
Università degli Studi di Torino (UNITO), Italy
Kirti Tiwari received her Bachelor’s degree in Physics (and minors in Chemistry and Zoology) from Carmel College for Women (India), in 2018.